1600 Pennsylvania Avenue, the most powerful address in the nation is now the focus of a homicide investigation. After the discovery of a young woman's slain body at the White House, jaded Washington DC detective Harlan Regis finds himself embroiled in a cover-up that may even reach the highest level of government. With the reluctant assistance of Secret Service agent Nina Chance, Regis searches for the truth amid a political scandal rife with suspects including National Security Advisor Alvin Jordan. Soon, Regis and Chance confront a situation far more dangerous than they could have imagined.